For me, lighter wheels are always faster, even a small reduction in weight makes a difference. I take an identical set of light <1 gram wheels and run one set regular and the other reversed.... the reversed is faster for me... I can tell the non-reversed are flexing during the transition. It really depends on how thin the vendor is cutting the tread area to determine when you must reverse the rears. What feels very flexible to the hand may not flex enough to be an issue when racing. I mean you only have a small amount of weight on the wheel (maybe 2 ounces max plus g force) and you are only flexing half the wheel (from OD to bore). So there is a sweet spot when you need to reverse, but I can't really tell you what number that is at because they are made different. The faster wheels, like DD4H wheels, you have to flip because most of the weight is taken from the OD to make the wheel the fastest. THe lever arm from the OD to the bore is longer so removing that weight makes the wheel easier to turn, less energy. Some other vendors <1 gram wheels are slow because they take a lot of weight off at the hub which does very little for speed.