It depends on what you mean....
I would clean the outer tread as often as possible, so after every race, no need to remove wheels from car for his step... Use superfine sandpaper followed by a soft cloth to remove dust, grime, and graphite from running surfaces. Clean wheels are fast wheels...
What are you lubricating with?
If you are running oil, you can probably run 50 to 100 runs without doing anything to the wheelbores.
If running graphite, I would add more graphite and see if your speed returns, if not tear down, clean everything, and reprep.
Is the car still fast? If so you probably don't need to do anything...